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In a accompanying note you, Dirk Sibbing and Dr Adnan Kastrati, Technische Universit t M nchen, Munich, Germany approved, that patients with a risk profile similar to patients in the TRITON-TIMI 38 study can be safely treated? proton pump inhibitor pump inhibitor to the top of the clopidogrel or prasugrel. They say: ‘Caution is required, however, when prescribing proton pump inhibitors in selected high-risk patients with intrinsic reduced response to thienopyridines. ‘ ‘Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomized trials ‘Michelle L O’Donoghue, Eugene Braunwald, Elliott M Antman, Sabina A Murphy, Eric R Bates, Yoseph Rozenman, Alan Michelson D, Raymond W Hautvast, Peter N Ver Lee, Sandra L close, Lei Shen, Jessica L Mega, Marc S Sabatine, Stephen D Wiviott DOI: 10.Continue Reading